What is one sign that may indicate discomfort or pain in an animal?

Increased vocalization and decreased appetite are both signs that can indicate discomfort or pain in an animal, making the combined answer the most comprehensive choice. Increased vocalization, such as whining, growling, or excessive barking, can suggest that the animal is experiencing distress or unhappiness, which can often correlate with pain. Animals are instinctively inclined to vocalize when they are hurt or uncomfortable as a way to communicate their state.

Decreased appetite is another significant indicator of pain or discomfort. Animals that are in pain may lose interest in food due to nausea or the association of eating with discomfort, or they may simply lack the energy to eat. A sustained decrease in appetite, especially when combined with other symptoms, can often point to an underlying health issue causing discomfort.

By choosing both increased vocalization and decreased appetite, it acknowledges that multiple signs can manifest simultaneously, providing a clearer picture of the animal’s well-being. This integrative view is crucial in veterinary practice when assessing an animal's health status.